There is an existing knowledge gap in the health of Asians, as only a handful of studies exist in this area. Immersed in and surrounded by the strong and rich scientific community of UCSF against the silhouette of a city with many Asians, the Asian Health Institute can provide a great venue for conducting clinical and translational research targeting the Asian community. This unique research focusing on Asians will hopefully help to advance the health care and health of Asians locally, and have implications nationwide as well as internationally. The focused venue will also support, encourage and spur interests of the existing expert investigators to develop clinical research studies for Asians, especially in disease areas that impact Asians most. Its distinctive presence also attracts international and national collaborations, generating a new exciting wave of unprecedented synergy in discovery.